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The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.
Genes Dev. 2011 Oct 15;25(20):2158-72. doi: 10.1101/gad.16962311.
Genes Dev. 2011.
PMID: 22012619
Free PMC article.
Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding.
Dixon-Clarke SE, Elkins JM, Cheng SW, Morin GB, Bullock AN.
Dixon-Clarke SE, et al.
Sci Rep. 2015 Nov 24;5:17122. doi: 10.1038/srep17122.
Sci Rep. 2015.
PMID: 26597175
Free PMC article.
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