Amultitude of glycosyltransferases (GTs), glycoside hydrolases (GHs; also called glycosidases), nucleotide sugar transporters, and other enzymes are required to synthesize and metabolize glycans. It follows that many genes in the genome are devoted to encoding these activities. In addition, many genes encode glycan-binding proteins (GBPs), which recognize specific glycan structures. This chapter provides a genomic perspective of the genes that code for GTs, GHs, and GBPs.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.