This chapter reviews the evidence for complex glycoconjugates in the nucleoplasmic and cytoplasmic compartments of the cell. The modification of nuclear and cytoplasmic proteins by a single β-linked N-acetylglucosamine (O-β-GlcNAc) is described in Chapter 18. Here the focus is on resident glycoproteins of the cytoplasm/nucleus with glycans of length two units or more. Current views regarding the putative functions of nuclear lectins and the possible roles of glycans as nuclear localization signals are also presented.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.