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A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat Struct Mol Biol. 2010 Jan;17(1):105-11. doi: 10.1038/nsmb.1719. Epub 2009 Dec 6.
Nat Struct Mol Biol. 2010.
PMID: 19966799
Free PMC article.
Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW.
Huttlin EL, et al.
Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.
Nature. 2017.
PMID: 28514442
Free PMC article.
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Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.
Liu H, Lu W, He H, Wu J, Zhang C, Gong H, Yang C.
Liu H, et al.
J Pathol. 2019 Aug;248(4):464-475. doi: 10.1002/path.5273. Epub 2019 Apr 22.
J Pathol. 2019.
PMID: 30945288
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