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RIOK3 interacts with caspase-10 and negatively regulates the NF-kappaB signaling pathway.
Mol Cell Biochem. 2009 Dec;332(1-2):113-20. doi: 10.1007/s11010-009-0180-8. Epub 2009 Jun 26.
Mol Cell Biochem. 2009.
PMID: 19557502
Toward an understanding of the protein interaction network of the human liver.
Wang J, Huo K, Ma L, Tang L, Li D, Huang X, Yuan Y, Li C, Wang W, Guan W, Chen H, Jin C, Wei J, Zhang W, Yang Y, Liu Q, Zhou Y, Zhang C, Wu Z, Xu W, Zhang Y, Liu T, Yu D, Zhang Y, Chen L, Zhu D, Zhong X, Kang L, Gan X, Yu X, Ma Q, Yan J, Zhou L, Liu Z, Zhu Y, Zhou T, He F, Yang X.
Wang J, et al.
Mol Syst Biol. 2011 Oct 11;7:536. doi: 10.1038/msb.2011.67.
Mol Syst Biol. 2011.
PMID: 21988832
Free PMC article.
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RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production.
Feng J, De Jesus PD, Su V, Han S, Gong D, Wu NC, Tian Y, Li X, Wu TT, Chanda SK, Sun R.
Feng J, et al.
J Virol. 2014 Jul;88(14):7987-97. doi: 10.1128/JVI.00643-14. Epub 2014 May 7.
J Virol. 2014.
PMID: 24807708
Free PMC article.
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RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.
Takashima K, Oshiumi H, Takaki H, Matsumoto M, Seya T.
Takashima K, et al.
Cell Rep. 2015 Apr 14;11(2):192-200. doi: 10.1016/j.celrep.2015.03.027.
Cell Rep. 2015.
PMID: 25865883
Free article.
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