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Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig.
Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6511-8. doi: 10.1073/pnas.0700899104. Epub 2007 Apr 11.
Proc Natl Acad Sci U S A. 2007.
PMID: 17428920
Free PMC article.
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Xu D, Wang Z, Xia Y, Shao F, Xia W, Wei Y, Li X, Qian X, Lee JH, Du L, Zheng Y, Lv G, Leu JS, Wang H, Xing D, Liang T, Hung MC, Lu Z.
Xu D, et al.
Nature. 2020 Apr;580(7804):530-535. doi: 10.1038/s41586-020-2183-2. Epub 2020 Apr 8.
Nature. 2020.
PMID: 32322062
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