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2005 1
2006 1
2011 1
2014 1
2017 1
2018 2
2024 0

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Page 1
Towards a proteome-scale map of the human protein-protein interaction network.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M. Rual JF, et al. Nature. 2005 Oct 20;437(7062):1173-8. doi: 10.1038/nature04209. Epub 2005 Sep 28. Nature. 2005. PMID: 16189514
Next-generation sequencing to generate interactome datasets.
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P, Vidal M. Yu H, et al. Nat Methods. 2011 Jun;8(6):478-80. doi: 10.1038/nmeth.1597. Epub 2011 Apr 24. Nat Methods. 2011. PMID: 21516116 Free PMC article.
The guanine-exchange factor Ric8a binds to the Ca²⁺ sensor NCS-1 to regulate synapse number and neurotransmitter release.
Romero-Pozuelo J, Dason JS, Mansilla A, Baños-Mateos S, Sardina JL, Chaves-Sanjuán A, Jurado-Gómez J, Santana E, Atwood HL, Hernández-Hernández Á, Sánchez-Barrena MJ, Ferrús A. Romero-Pozuelo J, et al. J Cell Sci. 2014 Oct 1;127(Pt 19):4246-59. doi: 10.1242/jcs.152603. Epub 2014 Jul 29. J Cell Sci. 2014. PMID: 25074811 Free article.
Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Mansilla A, Chaves-Sanjuan A, Campillo NE, Semelidou O, Martínez-González L, Infantes L, González-Rubio JM, Gil C, Conde S, Skoulakis EM, Ferrús A, Martínez A, Sánchez-Barrena MJ. Mansilla A, et al. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E999-E1008. doi: 10.1073/pnas.1611089114. Epub 2017 Jan 24. Proc Natl Acad Sci U S A. 2017. PMID: 28119500 Free PMC article.
Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
Roca C, Martinez-González L, Daniel-Mozo M, Sastre J, Infantes L, Mansilla A, Chaves-Sanjuan A, González-Rubio JM, Gil C, Cañada FJ, Martinez A, Sanchez-Barrena MJ, Campillo NE. Roca C, et al. J Med Chem. 2018 Jul 26;61(14):5910-5921. doi: 10.1021/acs.jmedchem.8b00088. Epub 2018 Jul 17. J Med Chem. 2018. PMID: 29966094