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Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin.
Schmelzer CEH, Heinz A, Troilo H, Lockhart-Cairns MP, Jowitt TA, Marchand MF, Bidault L, Bignon M, Hedtke T, Barret A, McConnell JC, Sherratt MJ, Germain S, Hulmes DJS, Baldock C, Muller L. Schmelzer CEH, et al. FASEB J. 2019 Apr;33(4):5468-5481. doi: 10.1096/fj.201801860RR. Epub 2019 Jan 24. FASEB J. 2019. PMID: 30676771 Free PMC article.
Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms.
Umana-Diaz C, Pichol-Thievend C, Marchand MF, Atlas Y, Salza R, Malbouyres M, Barret A, Teillon J, Ardidie-Robouant C, Ruggiero F, Monnot C, Girard P, Guilluy C, Ricard-Blum S, Germain S, Muller L. Umana-Diaz C, et al. Matrix Biol. 2020 Jun;88:33-52. doi: 10.1016/j.matbio.2019.11.003. Epub 2019 Nov 20. Matrix Biol. 2020. PMID: 31759052
LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity.
Almacellas-Rabaiget O, Monaco P, Huertas-Martinez J, García-Monclús S, Chicón-Bosch M, Maqueda-Marcos S, Fabra-Heredia I, Herrero-Martín D, Rello-Varona S, de Alava E, López-Alemany R, Giangrande PH, Tirado OM. Almacellas-Rabaiget O, et al. Cancer Lett. 2020 Apr 1;474:1-14. doi: 10.1016/j.canlet.2019.12.040. Epub 2020 Jan 3. Cancer Lett. 2020. PMID: 31911079