Abstract
Based on the pharmacological research of Chinese herbs on AD and some famous hypothesis on AD, such as dysfunction of nervous transmitter metabolism, apoptosis, inflammation etc, we consulted and analyzed relevant papers. We found the effective mechanism of Ginsenoside, Osthol, Rhodosin, and (-) Clausenamide were related to many pathological channels of AD, and Ginsenoside had effect on many pathological channels. The results have provided some clues for selecting effective herbs on AD.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Alzheimer Disease* / metabolism
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Alzheimer Disease* / pathology
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Amyloid beta-Peptides / biosynthesis
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Animals
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Apoptosis / drug effects
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Drugs, Chinese Herbal / isolation & purification
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Drugs, Chinese Herbal / pharmacology*
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Free Radical Scavengers / pharmacology
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Humans
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Learning / drug effects*
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Neurons / drug effects
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Neurotransmitter Agents / metabolism*
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Plants, Medicinal* / chemistry
Substances
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Amyloid beta-Peptides
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Drugs, Chinese Herbal
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Free Radical Scavengers
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Neurotransmitter Agents