Abstract
The group of peroxisomal disorders now includes 17 different disorders with Zellweger syndrome as prototype. Thanks to the explosion of new information about the functions and biogenesis of peroxisomes, the metabolic and molecular basis of most of the peroxisomal disorders has been resolved. A review of peroxisomal disorders is provided in this paper.
Copyright 2004 Wiley-Liss, Inc.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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ATPases Associated with Diverse Cellular Activities
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Fatty Acids / metabolism
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Humans
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Membrane Proteins / genetics
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Membrane Proteins / metabolism
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Models, Biological
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Oxidation-Reduction
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Peroxisomal Disorders / diagnosis
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Peroxisomal Disorders / genetics*
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Peroxisomal Disorders / metabolism*
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Peroxisomes / metabolism
Substances
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Fatty Acids
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Membrane Proteins
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ATPases Associated with Diverse Cellular Activities
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PEX1 protein, human