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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
J Biol Chem. 2003 Mar 28;278(13):11312-9. doi: 10.1074/jbc.M211609200. Epub 2002 Dec 19.
J Biol Chem. 2003.
PMID: 12496283
Free article.
Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids.
Stoddart LA, Smith NJ, Jenkins L, Brown AJ, Milligan G.
Stoddart LA, et al.
J Biol Chem. 2008 Nov 21;283(47):32913-24. doi: 10.1074/jbc.M805601200. Epub 2008 Sep 18.
J Biol Chem. 2008.
PMID: 18801738
Free article.
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