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Year | Number of Results |
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2002 | 1 |
2004 | 1 |
2011 | 2 |
2023 | 1 |
2024 | 0 |
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Page 1
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature. 2002 Apr 18;416(6882):703-9. doi: 10.1038/416703a.
Nature. 2002.
PMID: 11961546
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K, Nakayama KI.
Yada M, et al.
EMBO J. 2004 May 19;23(10):2116-25. doi: 10.1038/sj.emboj.7600217. Epub 2004 Apr 22.
EMBO J. 2004.
PMID: 15103331
Free PMC article.
Item in Clipboard
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W.
Gao D, et al.
Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030.
Mol Cell. 2011.
PMID: 22017875
Free PMC article.
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DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy.
Zhao Y, Xiong X, Sun Y.
Zhao Y, et al.
Mol Cell. 2011 Oct 21;44(2):304-16. doi: 10.1016/j.molcel.2011.08.029.
Mol Cell. 2011.
PMID: 22017876
Free PMC article.
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A central role for regulated protein stability in the control of TFE3 and MITF by nutrients.
Nardone C, Palanski BA, Scott DC, Timms RT, Barber KW, Gu X, Mao A, Leng Y, Watson EV, Schulman BA, Cole PA, Elledge SJ.
Nardone C, et al.
Mol Cell. 2023 Jan 5;83(1):57-73.e9. doi: 10.1016/j.molcel.2022.12.013.
Mol Cell. 2023.
PMID: 36608670
Free PMC article.
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