Pathogenicity islands and virulence evolution in Listeria

J A Vázquez-Boland; G Domínguez-Bernal; B González-Zorn; J Kreft; W Goebel

doi:10.1016/s1286-4579(01)01413-7

Pathogenicity islands and virulence evolution in Listeria

Microbes Infect. 2001 Jun;3(7):571-84. doi: 10.1016/s1286-4579(01)01413-7.

Authors

J A Vázquez-Boland¹, G Domínguez-Bernal, B González-Zorn, J Kreft, W Goebel

Affiliation

¹ Grupo de Patogénesis Molecular Bacteriana, Unidad de Microbiología e Inmunología, Departamento de Patología Animal I, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain. vazquez@eucmax.sim.ucm.es

PMID: 11418331
DOI: 10.1016/s1286-4579(01)01413-7

Abstract

As in other bacterial pathogens, the virulence determinants of Listeria species are clustered in genomic islands scattered along the chromosome. This review summarizes current knowledge about the structure, distribution and role in pathogenesis of Listeria virulence loci. Hypotheses about the mode of acquisition and evolution of these loci in this group of Gram-positive bacteria are presented and discussed.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Amino Acid Sequence
Animals
Bacterial Proteins / classification
Bacterial Proteins / genetics
Bacterial Proteins / physiology
Chromosomes, Bacterial / genetics
Evolution, Molecular
Humans
Listeria / genetics*
Listeria / pathogenicity*
Listeriosis / microbiology
Molecular Sequence Data
Multigene Family
Virulence / genetics

Substances

Bacterial Proteins
internalin protein, Bacteria