Protein Family Models

aquaporin family protein such as aquaporin, which is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2024-02-09

ICln is a ubiquitously expressed multi-functional protein that plays a critical role in regulating volume decrease in cells after cellular swelling. In plants, ICln induces Cl- currents [1,4,5], thus regulating Cl- homoeostasis in eukaryotes [2,3]. Structurally, the fold resembles a pleckstrin homology fold, on of whose roles is to recruit and tether their host protein to the cell membrane; and although the surface charges of the ICln fold are not equivalent to those of the PH domain, ICln can be phosphorylated in vitro and the PH-nature of the domain may be the part involving it in the transposition from cytosol to cell membrane during cytotonic swelling [1]. [1]. 16734741. The ICln interactome.. Furst J, Botta G, Saino S, Dopinto S, Gandini R, Dossena S,. Vezzoli V, Rodighiero S, Bazzini C, Garavaglia ML, Meyer G,. Jakab M, Ritter M, Wappl-Kornherr E, Paulmichl M;. Acta Physiol (Oxf). 2006;187:43-49.. [2]. 17138647. Hypotonicity induces aquaporin-2 internalization and. cytosol-to-membrane translocation of ICln in renal cells.. Tamma G, Procino G, Strafino A, Bononi E, Meyer G, Paulmichl M,. Formoso V, Svelto M, Valenti G;. Endocrinology. 2007;148:1118-1130.. [3]. 19471107. Quaternary structure assessment of ICln by fluorescence. resonance energy transfer (FRET) in vivo.. Schmidt S, Jakab M, Costa I, Furst J, Ravasio A, Paulmichl M,. Botta G, Ritter M;. Cell Physiol Biochem. 2009;23:397-406.. [4]. 20573047. Cl- homeostasis in includer and excluder citrus rootstocks:. transport mechanisms and identification of candidate genes.. Brumos J, Talon M, Bouhlal R, Colmenero-Flores JM;. Plant Cell Environ. 2010;33:2012-2027.. [5].. TRUNCATED at 1650 bytes (from Pfam)

Date:

2024-08-14

MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators [1]. [1]. 9655351. Prediction of functional residues in water channels and related. proteins.. Froger A, Tallur B, Thomas D, Delamarche C;. Protein Sci 1998;7:1458-1468. (from Pfam)

Date:

2024-08-14

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

Date:

2023-03-06

Gene:

aqpM

Date:

2021-11-05

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) domain-containing protein similar to Arabidopsis thaliana syntaxin-61 which coordinate the trafficking of plasma membrane aquaporin PIP2

Date:

2019-03-21

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) domain-containing protein similar to Arabidopsis thaliana syntaxin-61 which coordinate the trafficking of plasma membrane aquaporin PIP2

Date:

2017-03-02

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) domain-containing protein similar to Arabidopsis thaliana syntaxin-61 which coordinate the trafficking of plasma membrane aquaporin PIP2

Date:

2017-03-02

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

Date:

2024-07-01

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-06-07

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-06-07

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-06-07

TIP (tonoplast intrinsic protein)-type aquaporin is a water channel required to facilitate the transport of water from the vacuolar compartment to the cytoplasm

Date:

2023-03-06

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism; bifunctional GNAT family N-acetyltransferase/arsenate reductase ArsC which contains an N-terminal domain which may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate, and a C-terminal domain which may catalyze the reduction of arsenate [As(V)] to arsenite [As(III)]

Date:

2017-03-02

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-05-13

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-05-13

aquaporin is involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure

Date:

2016-05-13

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

Date:

2024-07-01

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) domain-containing protein similar to Arabidopsis thaliana syntaxin-61 which coordinate the trafficking of plasma membrane aquaporin PIP2

Date:

2017-03-02

aquaporin Z is involved in osmoregulation, allowing water to move into and out of the cell in response to osmotic pressure

Date:

2023-03-06