RecName: Full=Interferon-induced helicase C domain-containing protein - Protein

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The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner. [Front Immunol. 2024]
The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner.
Stock AJ, Gonzalez Paredes P, de Almeida LP, Kosanke SD, Chetlur S, Budde H, Wakenight P, Zwingman TA, Rosen ABI, Allenspach EJ, et al. Front Immunol. 2024; 15:1349601. Epub 2024 Feb 29.
MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival. [JCI Insight. 2023]
MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival.
Bullen CK, Singh AK, Krug S, Lun S, Thakur P, Srikrishna G, Bishai WR. JCI Insight. 2023 Oct 23; 8(20). Epub 2023 Oct 23.
Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double-Stranded RNA-Mediated IFN Response. [J Immunol. 2023]
Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double-Stranded RNA-Mediated IFN Response.
Miyamoto M, Himeda T, Ishihara K, Okuwa T, Kobayashi D, Nameta M, Karasawa Y, Chunhaphinyokul B, Yoshida Y, Tanaka N, et al. J Immunol. 2023 Feb 1; 210(3):335-347.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the Ifih1 gene.

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
reagents
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ExactAntigen/Labome

RecName: Full=Interferon-induced helicase C domain-containing protein 1; AltName...
RecName: Full=Interferon-induced helicase C domain-containing protein 1; AltName: Full=Helicase with 2 CARD domains; Short=Helicard; AltName: Full=Interferon induced with helicase C domain protein 1; AltName: Full=Melanoma differentiation-associated protein 5; Short=MDA-5; AltName: Full=RIG-I-like receptor 2; Short=RLR-2
gi|62510931|sp|Q8R5F7.1|IFIH1_MOUSE

Protein
Ifih1 interferon induced with helicase C domain 1 [Mus musculus]
Ifih1 interferon induced with helicase C domain 1 [Mus musculus]
Gene ID:71586

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Protein