Structure for Protein (Select 2217280946) - Structure - NCBI

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Select item 1549941.

Molecular Structure Image for 5WI2

Crystal structure of the KA1 domain from human Chk1[TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 3
modified:: 2023-10-10

MMDB ID:: 154994
PDB ID:: 5WI2

View in iCn3D Similar Structures PubMed Proteins PubChem Compound

Select item 1395112.

Molecular Structure Image for 5F4N

Multi-parameter lead optimization to give an oral CHK1 inhibitor clinical candidate: (R)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)[T...

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 8
modified:: 2024-05-13

MMDB ID:: 139511
PDB ID:: 5F4N

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1333883.

Molecular Structure Image for 5DLS

Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design[TRANSFERASE]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 2
modified:: 2024-01-16

MMDB ID:: 133388
PDB ID:: 5DLS

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1297054.

Molecular Structure Image for 4RVM

CHK1 kinase domain with diazacarbazole compound 19[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2023-09-30

MMDB ID:: 129705
PDB ID:: 4RVM

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1297045.

Molecular Structure Image for 4RVL

CHK1 kinase domain with diazacarbazole compound 7: 3-(2-hydroxyphenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2023-09-30

MMDB ID:: 129704
PDB ID:: 4RVL

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1297036.

Molecular Structure Image for 4RVK

CHK1 kinase domain with diazacarbazole compound 8: N-[3-(6-cyano-9H-pyrrolo[2,3-b:5,4-c']dipyridin-3-yl)phenyl]acetamide[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2023-09-30

MMDB ID:: 129703
PDB ID:: 4RVK

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1256327.

Molecular Structure Image for 4QYH

CHK1 kinase domain in complex with diazacarbazole GNE-783[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 125632
PDB ID:: 4QYH

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1256318.

Molecular Structure Image for 4QYG

CHK1 kinase domain in complex with diazacarbazole compound 14[Transferase/Transferase Inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 125631
PDB ID:: 4QYG

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 1256309.

Molecular Structure Image for 4QYF

CHK1 kinase domain in complex with aminopyrazine compound 13[Transferase/Transferase Inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 125630
PDB ID:: 4QYF

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 12562910.

Molecular Structure Image for 4QYE

CHK1 kinase domain in complex with diarylpyrazine compound 1[Transferase/Transferase Inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 125629
PDB ID:: 4QYE

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 10925311.

Molecular Structure Image for 4JIK

X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 109253
PDB ID:: 4JIK

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 10818112.

Molecular Structure Image for 4HYI

X-RAY Crystal structure of compound 40 bound to human chk1 kinase domain[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 4
modified:: 2024-03-05

MMDB ID:: 108181
PDB ID:: 4HYI

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 10818013.

Molecular Structure Image for 4HYH

X-RAY Crystal structure of compound 39 bound to human chk1 kinase domain[TRANSFERASE/TRANSFERASE INHIBITOR]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 1
modified:: 2024-03-05

MMDB ID:: 108180
PDB ID:: 4HYH

View in iCn3D Similar Structures PubMed Proteins Conserved Domains PubChem Compound

Select item 10358514.

Molecular Structure Image for 4GH2

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 6
modified:: 2023-12-11

MMDB ID:: 103585
PDB ID:: 4GH2

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10224415.

Molecular Structure Image for 4FTU

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 5
modified:: 2024-03-05

MMDB ID:: 102244
PDB ID:: 4FTU

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10224316.

Molecular Structure Image for 4FTT

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 5
modified:: 2024-03-05

MMDB ID:: 102243
PDB ID:: 4FTT

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10224217.

Molecular Structure Image for 4FTR

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 4
modified:: 2023-12-04

MMDB ID:: 102242
PDB ID:: 4FTR

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10224118.

Molecular Structure Image for 4FTQ

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 4
modified:: 2023-12-04

MMDB ID:: 102241
PDB ID:: 4FTQ

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10224019.

Molecular Structure Image for 4FTO

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 5
modified:: 2023-12-04

MMDB ID:: 102240
PDB ID:: 4FTO

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

Select item 10223920.

Molecular Structure Image for 4FTN

Crystal Structure of the CHK1[TRANSFERASE/TRANSFERASE inhibitor]

Taxonomy:: Homo sapiens

Proteins:: 1
Chemicals:: 5
modified:: 2023-12-04

MMDB ID:: 102239
PDB ID:: 4FTN

View in iCn3D Similar Structures Proteins Conserved Domains PubChem Compound

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Protein Domain Families

Families (112)
Structures with functionally specific protein families
Superfamilies (112)
Structures with evolutionary related protein superfamilies

Complexes

Protein-Protein (4)
Structures containing multiple proteins
Protein-Chemical (113)
Structures containing proteins and chemicals

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PubMed (79)
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Structure for Protein (Select 2217280946) (113)
Structure
Gene Links for Protein (Select 1943293572) (1)
Gene
H1225_RS05420 [Proteus penneri]
H1225_RS05420 [Proteus penneri]
Gene ID:76522677

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