WD repeat and FYVE domain-containing protein 3 isoform X3 [Homo sapien - Protein

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View conserved domains detected in this protein sequence using CD-search.

ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration. [J Cell Sci. 2022]
ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration.
Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A. J Cell Sci. 2022 Feb 15; 135(4). Epub 2022 Feb 18.
A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance. [Traffic. 2021]
A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance.
Reinhart EF, Litt NA, Katzenell S, Pellegrini M, Yamamoto A, Ragusa MJ. Traffic. 2021 Jan; 22(1-2):23-37. Epub 2020 Dec 1.
Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. [Brain. 2019]
Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size.
Le Duc D, Giulivi C, Hiatt SM, Napoli E, Panoutsopoulos A, Harlan De Crescenzo A, Kotzaeridou U, Syrbe S, Anagnostou E, Azage M, et al. Brain. 2019 Sep 1; 142(9):2617-2630.

RefSeq genomic sequence
See the genomic reference sequence for the WDFY3 gene (NG_046917.1).
RefSeq mRNA
See reference mRNA sequence for the WDFY3 gene (XM_054349324.1).

Chain V, TFIIH basal transcription factor complex helicase XPB subunit
Chain V, TFIIH basal transcription factor complex helicase XPB subunit
gi|1028909827|pdb|5IY8|V

Protein
Homo sapiens integrin subunit beta 2 (ITGB2), transcript variant 2, mRNA
Homo sapiens integrin subunit beta 2 (ITGB2), transcript variant 2, mRNA
gi|1675021966|ref|NM_001127491.3|

Nucleotide

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Protein