shieldin complex subunit 1 isoform X2 [Homo sapiens]

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MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair. [Nat Commun. 2021]
MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair.
de Krijger I, Föhr B, Pérez SH, Vincendeau E, Serrat J, Thouin AM, Susvirkar V, Lescale C, Paniagua I, Hoekman L, et al. Nat Commun. 2021 Sep 14; 12(1):5421. Epub 2021 Sep 14.
Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action. [Cell Rep. 2021]
Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action.
Isobe SY, Hiraga SI, Nagao K, Sasanuma H, Donaldson AD, Obuse C. Cell Rep. 2021 Jul 13; 36(2):109383.
53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis. [Nat Cell Biol. 2022]
53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis.
Mirman Z, Sasi NK, King A, Chapman JR, de Lange T. Nat Cell Biol. 2022 Jan; 24(1):51-61. Epub 2022 Jan 13.

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