protein NLRC5 isoform X2 [Mus musculus]

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NLRC5 senses NAD(+) depletion, forming a PANoptosome and driving PANoptosis and inflammation. [Cell. 2024]
NLRC5 senses NAD(+) depletion, forming a PANoptosome and driving PANoptosis and inflammation.
Sundaram B, Pandian N, Kim HJ, Abdelaal HM, Mall R, Indari O, Sarkar R, Tweedell RE, Alonzo EQ, Klein J, et al. Cell. 2024 Jul 25; 187(15):4061-4077.e17. Epub 2024 Jun 14.
NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-κB Signaling and Ameliorates Mice's Depressive-like Behavior. [Int J Mol Sci. 2023]
NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-κB Signaling and Ameliorates Mice's Depressive-like Behavior.
Sun C, Shen Y, Liu P, Shen Y, Hu Y, Li P, Zhang Y, Miao F, Zhang J. Int J Mol Sci. 2023 Aug 26; 24(17). Epub 2023 Aug 26.
NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson's disease models. [J Neuroinflammation. 2023]
NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson's disease models.
Liu Z, Shen C, Li H, Tong J, Wu Y, Ma Y, Wang J, Wang Z, Li Q, Zhang X, et al. J Neuroinflammation. 2023 Apr 18; 20(1):96. Epub 2023 Apr 18.

RefSeq mRNA
See reference mRNA sequence for the Nlrc5 gene (XM_006531165.3).
RefSeq protein isoforms
See 6 reference sequence protein isoforms for the Nlrc5 gene.

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Protein