RecName: Full=Interferon-induced helicase C domain-containing protein - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus. [Proc Natl Acad Sci U S A. 2024]
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2404349121. Epub 2024 Jul 10.
Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022. [Clin Rheumatol. 2024]
Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022.
Yuan X, Shi J, Peng Z, Peng L, Zhou S, Wu C, Zhao J, Xu D, Li M, Wang Q, et al. Clin Rheumatol. 2024 Mar; 43(3):1111-1126. Epub 2024 Jan 6.
Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. [FEBS J. 2024]
Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes.
Dansako H, Ikeda M, Ariumi Y, Togashi Y, Kato N. FEBS J. 2024 Mar; 291(6):1119-1130. Epub 2023 Oct 27.

RefSeq genomic sequence
See the genomic reference sequence for the IFIH1 gene (NG_011495.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the IFIH1 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Interferon-induced helicase C domain-containing protein 1; AltName...
RecName: Full=Interferon-induced helicase C domain-containing protein 1; AltName: Full=Clinically amyopathic dermatomyositis autoantigen 140 kDa; Short=CADM-140 autoantigen; AltName: Full=Helicase with 2 CARD domains; Short=Helicard; AltName: Full=Interferon-induced with helicase C domain protein 1; AltName: Full=Melanoma differentiation-associated protein 5; Short=MDA-5; AltName: Full=Murabutide down-regulated protein; AltName: Full=RIG-I-like receptor 2; Short=RLR-2; AltName: Full=RNA helicase-DEAD box protein 116
gi|134047802|sp|Q9BYX4.3|IFIH1_HUMA

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein