RecName: Full=Isoaspartyl peptidase/L-asparaginase; AltName: Full=Aspa - Protein

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l-Asparaginase regulates mTORC1 activity via a TSC2-dependent pathway in pancreatic beta cells. [Biochem Biophys Res Commun. 2023]
l-Asparaginase regulates mTORC1 activity via a TSC2-dependent pathway in pancreatic beta cells.
Seike M, Asahara SI, Inoue H, Kudo M, Kanno A, Yokoi A, Suzuki H, Kimura-Koyanagi M, Kido Y, Ogawa W. Biochem Biophys Res Commun. 2023 Apr 16; 652:121-130. Epub 2023 Feb 16.
ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner. [Dig Liver Dis. 2023]
ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner.
Wang X, Wang Y, Yang L, Yuan J, Shen W, Zhang W, Wang J, Tao K. Dig Liver Dis. 2023 Jul; 55(7):955-966. Epub 2022 Dec 24.
TRABID targets DDB2 for deubiquitination to promote proliferation of hepatocellular carcinoma cells. [Biochem Biophys Res Commun. 2022]
TRABID targets DDB2 for deubiquitination to promote proliferation of hepatocellular carcinoma cells.
Chen Y, Zhang X. Biochem Biophys Res Commun. 2022 Oct 15; 625:23-30. Epub 2022 Aug 2.

RefSeq protein isoforms
See 10 reference sequence protein isoforms for the ASRGL1 gene.

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Q7L266 [Domain Mapping of Disease Mut...]
Q7L266
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Isoaspartyl peptidase/L-asparaginase; AltName: Full=Asparaginase-l...
RecName: Full=Isoaspartyl peptidase/L-asparaginase; AltName: Full=Asparaginase-like protein 1; AltName: Full=Beta-aspartyl-peptidase; AltName: Full=Isoaspartyl dipeptidase; AltName: Full=L-asparagine amidohydrolase; Contains: RecName: Full=Isoaspartyl peptidase/L-asparaginase alpha chain; Contains: RecName: Full=Isoaspartyl peptidase/L-asparaginase beta chain; Flags: Precursor
gi|158706477|sp|Q7L266.2|ASGL1_HUMA

Protein
Autosomal dominant distal renal tubular acidosis
Autosomal dominant distal renal tubular acidosis

MedGen
Pseudohypoaldosteronism type 2C
Pseudohypoaldosteronism type 2C

MedGen

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Protein