RecName: Full=Sialic acid-binding Ig-like lectin 15; Short=Siglec-15; - Protein

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SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion. [Oncoimmunology. 2024]
SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion.
Chen Z, Yu M, Zhang B, Jin L, Yu Q, Liu S, Zhou B, Yan J, Zhang W, Li X, et al. Oncoimmunology. 2024; 13(1):2376264. Epub 2024 Jul 9.
Siglec-15 regulates cell proliferation, migration and invasion in bladder cancer. [Asian J Surg. 2024]
Siglec-15 regulates cell proliferation, migration and invasion in bladder cancer.
Gao HY, Liu GJ, Qiu YR. Asian J Surg. 2024 Apr; 47(4):1892-1894. Epub 2024 Jan 2.
Siglec-15 on macrophages suppress the immune microenvironment in patients with PD-L1 negative non-metastasis lung adenocarcinoma. [Cancer Gene Ther. 2024]
Siglec-15 on macrophages suppress the immune microenvironment in patients with PD-L1 negative non-metastasis lung adenocarcinoma.
Huang Z, Guo Y, Li B, Shen M, Yi Y, Li L, Zhao X, Yang L. Cancer Gene Ther. 2024 Mar; 31(3):427-438. Epub 2023 Dec 11.

RefSeq protein
See the reference protein sequence for sialic acid-binding Ig-like lectin 15 precursor (NP_998767.1).

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Q6ZMC9 [Domain Mapping of Disease Mut...]
Q6ZMC9
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
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Reactome
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ExactAntigen/Labome

RecName: Full=Sialic acid-binding Ig-like lectin 15; Short=Siglec-15; AltName: F...
RecName: Full=Sialic acid-binding Ig-like lectin 15; Short=Siglec-15; AltName: Full=CD33 antigen-like 3; Flags: Precursor
gi|74762385|sp|Q6ZMC9.1|SIG15_HUMAN

Protein
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SYNJ1 [Pongo abelii]
Gene ID:100437498

Gene
AWJ20_1302 [Sugiyamaella lignohabitans]
AWJ20_1302 [Sugiyamaella lignohabitans]
Gene ID:30033090

Gene
HTUR_RS21875 [Haloterrigena turkmenica DSM 5511]
HTUR_RS21875 [Haloterrigena turkmenica DSM 5511]
Gene ID:8745099

Gene
N7525_002400 [Penicillium rubens]
N7525_002400 [Penicillium rubens]
Gene ID:8308749

Gene

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Protein