RecName: Full=Tyrosyl-DNA phosphodiesterase 2; Short=Tyr-DNA phosphodi - Protein

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An RNA virus hijacks an incognito function of a DNA repair enzyme. [Proc Natl Acad Sci U S A. 2012]
An RNA virus hijacks an incognito function of a DNA repair enzyme.
Virgen-Slane R, Rozovics JM, Fitzgerald KD, Ngo T, Chou W, van der Heden van Noort GJ, Filippov DV, Gershon PD, Semler BL. Proc Natl Acad Sci U S A. 2012 Sep 4; 109(36):14634-9. Epub 2012 Aug 20.
Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes. [J Biol Chem. 2012]
Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.
Gao R, Huang SY, Marchand C, Pommier Y. J Biol Chem. 2012 Aug 31; 287(36):30842-52. Epub 2012 Jul 20.
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. [Nat Genet. 2014]
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
Gómez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, et al. Nat Genet. 2014 May; 46(5):516-21. Epub 2014 Mar 23.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the Tdp2 gene.

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