RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH - Protein

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The scorpion toxin BeKm-1 blocks hERG cardiac potassium channels using an indispensable arginine residue. [FEBS Lett. 2024]
The scorpion toxin BeKm-1 blocks hERG cardiac potassium channels using an indispensable arginine residue.
Zavarzina II, Kuzmenkov AI, Dobrokhotov NA, Maleeva EE, Korolkova YV, Peigneur S, Tytgat J, Krylov NA, Vassilevski AA, Chugunov AO. FEBS Lett. 2024 Apr; 598(8):889-901. Epub 2024 Apr 2.
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG. [BMC Biol. 2024]
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG.
Liu Z, Wang F, Yuan H, Tian F, Yang C, Hu F, Liu Y, Tang M, Ping M, Kang C, et al. BMC Biol. 2024 Feb 5; 22(1):29. Epub 2024 Feb 5.
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch-clamp assay. [HGG Adv. 2024]
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch-clamp assay.
Thomson KL, Jiang C, Richardson E, Westphal DS, Burkard T, Wolf CM, Vatta M, Harrison SM, Ingles J, Bezzina CR, et al. HGG Adv. 2024 Apr 11; 5(2):100270. Epub 2024 Jan 14.

RefSeq genomic sequence
See the genomic reference sequence for the KCNH2 gene (NG_008916.1).
RefSeq protein isoforms
See 18 reference sequence protein isoforms for the KCNH2 gene.

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Q12809 [Domain Mapping of Disease Mut...]
Q12809
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
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reagent reviews [ExactAntigen/Labome]
reagent reviews
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RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH2; AltName...
RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH2; AltName: Full=Eag homolog; AltName: Full=Ether-a-go-go-related gene potassium channel 1; Short=ERG-1; Short=Eag-related protein 1; Short=Ether-a-go-go-related protein 1; Short=H-ERG; Short=hERG-1; Short=hERG1; AltName: Full=Potassium voltage-gated channel subfamily H member 2; AltName: Full=Voltage-gated potassium channel subunit Kv11.1
gi|7531135|sp|Q12809.1|KCNH2_HUMAN

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