RecName: Full=NACHT, LRR and PYD domains-containing protein 6; AltName - Protein

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Decreased expression of the NLRP6 inflammasome is associated with increased intestinal permeability and inflammation in obesity with type 2 diabetes. [Cell Mol Life Sci. 2024]
Decreased expression of the NLRP6 inflammasome is associated with increased intestinal permeability and inflammation in obesity with type 2 diabetes.
Frühbeck G, Gómez-Ambrosi J, Ramírez B, Becerril S, Rodríguez A, Mentxaka A, Valentí V, Moncada R, Reina G, Baixauli J, et al. Cell Mol Life Sci. 2024 Feb 5; 81(1):77. Epub 2024 Feb 5.
NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment. [Biochim Biophys Acta Mol Basis...]
NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment.
Chang L, Xu L, Tian Y, Liu Z, Song M, Li S, Zhang X, Chen Y, Hao Q, Lu Y, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Mar; 1870(3):167035. Epub 2024 Jan 25.
NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis. [Nat Commun. 2023]
NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis.
Zhi F, Li B, Zhang C, Xia F, Wang R, Xie W, Cai S, Zhang D, Kong R, Hu Y, et al. Nat Commun. 2023 Sep 28; 14(1):6069. Epub 2023 Sep 28.

RefSeq genomic sequence
See the genomic reference sequence for the NLRP6 gene (NG_050573.1).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the NLRP6 gene.

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P59044 [Domain Mapping of Disease Mut...]
P59044
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

delta(12)-acyl-lipid-desaturase [Helianthus annuus]
delta(12)-acyl-lipid-desaturase [Helianthus annuus]
gi|1228823027|ref|XP_021970167.1|

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Protein