RecName: Full=Tripeptidyl-peptidase 1; Short=TPP-1; AltName: Full=Cell - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

CLN2 disease resulting from a novel homozygous deep intronic splice variant in TPP1 discovered using long-read sequencing. [Mol Genet Metab. 2023]
CLN2 disease resulting from a novel homozygous deep intronic splice variant in TPP1 discovered using long-read sequencing.
Steigerwald C, Borsuk J, Pappas J, Galey M, Scott A, Devaney JM, Miller DE, Abreu NJ. Mol Genet Metab. 2023 Dec; 140(4):107713. Epub 2023 Oct 30.
TPP1 Inhibits DNA Damage Response and Chemosensitivity in Esophageal Cancer. [Crit Rev Eukaryot Gene Expr. 2...]
TPP1 Inhibits DNA Damage Response and Chemosensitivity in Esophageal Cancer.
Wen J, Zhong X, Gao C, Yang M, Tang M, Yuan Z, Wang Q, Xu L, Ma Q, Guo X, et al. Crit Rev Eukaryot Gene Expr. 2023; 33(8):77-91.
Magnetic resonance brain volumetry biomarkers of CLN2 Batten disease identified with miniswine model. [Sci Rep. 2023]
Magnetic resonance brain volumetry biomarkers of CLN2 Batten disease identified with miniswine model.
Knoernschild K, Johnson HJ, Schroeder KE, Swier VJ, White KA, Sato TS, Rogers CS, Weimer JM, Sieren JC. Sci Rep. 2023 Mar 29; 13(1):5146. Epub 2023 Mar 29.

RefSeq genomic sequence
See the genomic reference sequence for the TPP1 gene (NG_008653.1).
RefSeq protein
See the reference protein sequence for tripeptidyl-peptidase 1 preproprotein (NP_000382.3).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

O14773 [Domain Mapping of Disease Mut...]
O14773
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Your browsing activity is empty.

Activity recording is turned off.

Protein