tyrosine-protein phosphatase non-receptor type 2 isoform 2 [Homo sapie - Protein

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Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus. [J Exp Med. 2024]
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus.
Jeanpierre M, Cognard J, Tusseau M, Riller Q, Bui LC, Berthelet J, Laurent A, Crickx E, Parlato M, Stolzenberg MC, et al. J Exp Med. 2024 Sep 2; 221(9). Epub 2024 Jul 19.
Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity. [Cells. 2022]
Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity.
Triolo TM, Matuschek JQ, Castro-Gutierrez R, Shilleh AH, Williams SPM, Hansen MS, McDaniel K, Barra JM, Michels A, Russ HA. Cells. 2022 Nov 30; 11(23). Epub 2022 Nov 30.
PTPN2 in the Immunity and Tumor Immunotherapy: A Concise Review. [Int J Mol Sci. 2022]
PTPN2 in the Immunity and Tumor Immunotherapy: A Concise Review.
Song J, Lan J, Tang J, Luo N. Int J Mol Sci. 2022 Sep 2; 23(17). Epub 2022 Sep 2.

RefSeq genomic sequence
See the genomic reference sequence for the PTPN2 gene (NG_029116.1).
RefSeq mRNA
See reference mRNA sequence for the PTPN2 gene (NM_080422.3).
RefSeq protein isoforms
See 17 reference sequence protein isoforms for the PTPN2 gene.

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Nucleotide
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SNP
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NP_536347 [Domain Mapping of Disease Mut...]
NP_536347
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Klebsiella variicola strain L1_54_7 NODE_31_length_4632_cov_102.870472, whole ge...
Klebsiella variicola strain L1_54_7 NODE_31_length_4632_cov_102.870472, whole genome shotgun sequence
gi|2469882463|ref|NZ_JAQTIH01000003 gnl|WGS:NZ_JAQTIH01|NODE_31_length_4632_cov_102.870472

Nucleotide
PREDICTED: solute carrier family 35 member G2 [Balearica regulorum gibbericeps]
PREDICTED: solute carrier family 35 member G2 [Balearica regulorum gibbericeps]
gi|723568744|ref|XP_010304633.1|

Protein
SRX2185321 (1)
SRA

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