presenilin-2 isoform 1 [Mus musculus]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Loss of normal Alzheimer's disease-associated Presenilin 2 function alters antiseizure medicine potency and tolerability in the 6-Hz focal seizure model. [Front Neurol. 2023]
Loss of normal Alzheimer's disease-associated Presenilin 2 function alters antiseizure medicine potency and tolerability in the 6-Hz focal seizure model.
Lehmann LM, Barker-Haliski M. Front Neurol. 2023; 14:1223472. Epub 2023 Aug 1.
Chronic seizures induce sex-specific cognitive deficits with loss of presenilin 2 function. [Exp Neurol. 2023]
Chronic seizures induce sex-specific cognitive deficits with loss of presenilin 2 function.
Knox KM, Beckman M, Smith CL, Jayadev S, Barker-Haliski M. Exp Neurol. 2023 Mar; 361:114321. Epub 2023 Jan 9.
Exercise Reverses Amyloid β-Peptide-Mediated Cognitive Deficits in Alzheimer's Disease Mice Expressing Mutant Presenilin-2. [Med Sci Sports Exerc. 2022]
Exercise Reverses Amyloid β-Peptide-Mediated Cognitive Deficits in Alzheimer's Disease Mice Expressing Mutant Presenilin-2.
Hwang DJ, Choi DH, Kwon KC, Kim EH, Kim TK, Koo JH, Cho JY. Med Sci Sports Exerc. 2022 Apr 1; 54(4):551-565.

RefSeq mRNA
See reference mRNA sequence for the Psen2 gene (NM_011183.4).
RefSeq protein isoforms
See 6 reference sequence protein isoforms for the Psen2 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
presenilin 2 protein [Guide to Pharmacology]
presenilin 2 protein
Guide to Pharmacology
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

693569[uid] (1)
Taxonomy
VPS35L[gene] (46)
ClinVar
presenilin-2 isoform 2 [Mus musculus]
presenilin-2 isoform 2 [Mus musculus]
gi|2499879669|ref|NP_001407399.1|

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein