Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.
Li HD, Cuevas I, Zhang M, Lu C, Alam MM, Fu YX, You MJ, Akbay EA, Zhang H, Castrillon DH. J Clin Invest. 2018 Aug 31; 128(9):4179-4191. Epub 2018 Aug 20.