neurogenic locus notch homolog protein 3 precursor [Mus musculus]

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Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL. [J Clin Invest. 2024]
Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL.
Dupré N, Gueniot F, Domenga-Denier V, Dubosclard V, Nilles C, Hill-Eubanks D, Morgenthaler-Roth C, Nelson MT, Keime C, Danglot L, et al. J Clin Invest. 2024 Feb 22; 134(8). Epub 2024 Feb 22.
Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice. [J Clin Invest. 2024]
Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.
Romay MC, Knutsen RH, Ma F, Mompeón A, Hernandez GE, Salvador J, Mirkov S, Batra A, Sullivan DP, Procissi D, et al. J Clin Invest. 2024 Jan 16; 134(2). Epub 2024 Jan 16.
Antisense oligonucleotides targeting a NOTCH3 mutation in male mice ameliorate the cortical osteopenia of lateral meningocele syndrome. [Bone. 2023]
Antisense oligonucleotides targeting a NOTCH3 mutation in male mice ameliorate the cortical osteopenia of lateral meningocele syndrome.
Canalis E, Mocarska M, Schilling L, Jafar-Nejad P, Carrer M. Bone. 2023 Dec; 177:116898. Epub 2023 Sep 11.

RefSeq mRNA
See reference mRNA sequence for the Notch3 gene (NM_008716.3).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the Notch3 gene.

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Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

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Protein