DNA-binding protein Ikaros isoform 1 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children. [Cell Genom. 2024]
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.
de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, et al. Cell Genom. 2024 Apr 10; 4(4):100526. Epub 2024 Mar 26.
IKAROS gain of function disease: Allogeneic hematopoietic cell transplantation experience and expanded clinical phenotypes. [Clin Immunol. 2024]
IKAROS gain of function disease: Allogeneic hematopoietic cell transplantation experience and expanded clinical phenotypes.
Klangkalya N, Stoddard J, Niemela J, Sponaugle J, Greenwell IB, Reigh E, Kuehn HS, Kanakry JA, Rosenzweig SD, Dimitrova D. Clin Immunol. 2024 Mar; 260:109922. Epub 2024 Feb 5.
Pediatric Necrobiotic Xanthogranuloma as a Novel Phenotype of IKAROS Gain of Function. [J Clin Immunol. 2023]
Pediatric Necrobiotic Xanthogranuloma as a Novel Phenotype of IKAROS Gain of Function.
Guess R, Harocopos G, Bednarski JJ, Hassmann LM, Bigley TM. J Clin Immunol. 2023 Dec 22; 44(1):19. Epub 2023 Dec 22.

RefSeq genomic sequence
See the genomic reference sequence for the IKZF1 gene (NG_034231.1).
RefSeq mRNA
See reference mRNA sequence for the IKZF1 gene (NM_006060.6).
RefSeq protein isoforms
See 105 reference sequence protein isoforms for the IKZF1 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_006051 [Domain Mapping of Disease Mut...]
NP_006051
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

Your browsing activity is empty.

Activity recording is turned off.

Protein