serine/threonine-protein kinase PAK 1 isoform 2 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis. [Cell Rep. 2023]
PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis.
Jokl E, Mullan AF, Simpson K, Birchall L, Pearmain L, Martin K, Pritchett J, Raza S, Shah R, Hodson NW, et al. Cell Rep. 2023 Nov 28; 42(11):113414. Epub 2023 Nov 14.
PAK1 and Therapy Resistance in Melanoma. [Cells. 2023]
PAK1 and Therapy Resistance in Melanoma.
Kichina JV, Maslov A, Kandel ES. Cells. 2023 Sep 28; 12(19). Epub 2023 Sep 28.
A PAK1 Mutational Hotspot Within the Regulatory CRIPaK Domain is Associated With Severe Neurodevelopmental Disorders in Children. [Pediatr Neurol. 2023]
A PAK1 Mutational Hotspot Within the Regulatory CRIPaK Domain is Associated With Severe Neurodevelopmental Disorders in Children.
Scorrano G, D'Onofrio G, Accogli A, Severino M, Buchert R, Kotzaeridou U, Iapadre G, Farello G, Iacomino M, Dono F, et al. Pediatr Neurol. 2023 Dec; 149:84-92. Epub 2023 Sep 16.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (List)
PubChem BioAssays done on the protein target
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_002567 [Domain Mapping of Disease Mut...]
NP_002567
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Your browsing activity is empty.

Activity recording is turned off.

Protein