growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1 - Protein

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Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML. [Blood. 2024]
Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML.
Hassan N, Yi H, Malik B, Gaspard-Boulinc L, Samaraweera SE, Casolari DA, Seneviratne J, Balachandran A, Chew T, Duly A, et al. Blood. 2024 Jul 4; 144(1):84-98.
GADD45A is a mediator of mitochondrial loss, atrophy, and weakness in skeletal muscle. [JCI Insight. 2023]
GADD45A is a mediator of mitochondrial loss, atrophy, and weakness in skeletal muscle.
Marcotte GR, Miller MJ, Kunz HE, Ryan ZC, Strub MD, Vanderboom PM, Heppelmann CJ, Chau S, Von Ruff ZD, Kilroe SP, et al. JCI Insight. 2023 Nov 22; 8(22). Epub 2023 Nov 22.
Gadd45 in Normal Hematopoiesis and Leukemia. [Adv Exp Med Biol. 2022]
Gadd45 in Normal Hematopoiesis and Leukemia.
Liebermann DA. Adv Exp Med Biol. 2022; 1360:41-54.

RefSeq mRNA
See reference mRNA sequence for the GADD45A gene (NM_001924.4).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the GADD45A gene.

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NP_001915 [Domain Mapping of Disease Mut...]
NP_001915
Domain Mapping of Disease Mutations
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OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
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Protein