tyrosine-protein kinase SYK isoform Syk(S) [Homo sapiens]

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DNA hypomethylation of Syk induces oxidative stress and apoptosis via the PKCβ/P66shc signaling pathway in diabetic kidney disease. [FASEB J. 2024]
DNA hypomethylation of Syk induces oxidative stress and apoptosis via the PKCβ/P66shc signaling pathway in diabetic kidney disease.
Zhang R, Qin C, Zhang J, HonghongRen, Wang Y, Wu Y, Zhao L, Wang J, Zhang J, Liu F. FASEB J. 2024 Mar 31; 38(6):e23564.
Spleen tyrosine kinase facilitates the progression of papillary thyroid cancer regulated by the hsa_circ_0006417/miR-377-3p axis. [Environ Toxicol. 2024]
Spleen tyrosine kinase facilitates the progression of papillary thyroid cancer regulated by the hsa_circ_0006417/miR-377-3p axis.
Tan G, Zheng S, Zhou B, Mo Z, Zhang Q, Zhang D, Li A, Liu X. Environ Toxicol. 2024 Jan; 39(1):421-434. Epub 2023 Oct 4.
Mast cells are upregulated in hidradenitis suppurativa tissue, associated with epithelialized tunnels and normalized by spleen tyrosine kinase antagonism. [Exp Dermatol. 2024]
Mast cells are upregulated in hidradenitis suppurativa tissue, associated with epithelialized tunnels and normalized by spleen tyrosine kinase antagonism.
Flora A, Jepsen R, Kozera EK, Woods JA, Cains GD, Radzieta M, Jensen SO, Malone M, Frew JW. Exp Dermatol. 2024 Jan; 33(1):e14894. Epub 2023 Jul 31.

RefSeq genomic sequence
See the genomic reference sequence for the SYK gene (NG_017046.2).
RefSeq mRNA
See reference mRNA sequence for the SYK gene (NM_001135052.4).
RefSeq protein isoforms
See 13 reference sequence protein isoforms for the SYK gene.

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NP_001128524
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
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reagents [ExactAntigen/Labome]
reagents
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reagent reviews
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