Chromosome 14 open reading frame 142 [Homo sapiens]

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Defects in t(6)A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome. [Nat Commun. 2019]
Defects in t(6)A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.
Arrondel C, Missoury S, Snoek R, Patat J, Menara G, Collinet B, Liger D, Durand D, Gribouval O, Boyer O, et al. Nat Commun. 2019 Sep 3; 10(1):3967. Epub 2019 Sep 3.
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. [Nucleic Acids Res. 2017]
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
Wan LC, Maisonneuve P, Szilard RK, Lambert JP, Ng TF, Manczyk N, Huang H, Laister R, Caudy AA, Gingras AC, et al. Nucleic Acids Res. 2017 Jan 25; 45(2):805-817. Epub 2016 Nov 29.
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. [PLoS One. 2012]
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME.
Costessi A, Mahrour N, Sharma V, Stunnenberg R, Stoel MA, Tijchon E, Conaway JW, Conaway RC, Stunnenberg HG. PLoS One. 2012; 7(8):e42822. Epub 2012 Aug 13.

RefSeq genomic sequence
See the genomic reference sequence for the GON7 gene (NG_051089.1).

Nucleotide
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Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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