RecName: Full=Complement C4-A; AltName: Full=Acidic complement C4; Alt - Protein

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Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. [Genome Biol. 2023]
Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth.
Hernandez LM, Kim M, Zhang P, Bethlehem RAI, Hoftman G, Loughnan R, Smith D, Bookheimer SY, Fan CC, Bearden CE, et al. Genome Biol. 2023 Mar 7; 24(1):42. Epub 2023 Mar 7.
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia. [Nat Commun. 2022]
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.
Gracias J, Orhan F, Hörbeck E, Holmén-Larsson J, Khanlarkani N, Malwade S, Goparaju SK, Schwieler L, Demirel İŞ, Fu T, et al. Nat Commun. 2022 Nov 3; 13(1):6427. Epub 2022 Nov 3.
Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders. [Neurobiol Dis. 2022]
Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders.
Mou TM, Lane MV, Ireland DDC, Verthelyi D, Tonelli LH, Clark SM. Neurobiol Dis. 2022 Oct 15; 173:105840. Epub 2022 Aug 19.

RefSeq genomic sequence
See the genomic reference sequence for the C4A gene (NG_011638.1).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the C4A gene.

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Related structures

P0C0L4 [Domain Mapping of Disease Mut...]
P0C0L4
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Complement C4-A; AltName: Full=Acidic complement C4; AltName: Full...
RecName: Full=Complement C4-A; AltName: Full=Acidic complement C4; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; Contains: RecName: Full=Complement C4 beta chain; Contains: RecName: Full=Complement C4-A alpha chain; Contains: RecName: Full=C4a anaphylatoxin; Contains: RecName: Full=C4b-A; Contains: RecName: Full=C4d-A; Contains: RecName: Full=Complement C4 gamma chain; Flags: Precursor
gi|476007827|sp|P0C0L4.2|CO4A_HUMAN

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