RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE1; A - Protein

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TurboID-Based IRE1 Interactome Reveals Participants of the Endoplasmic Reticulum-Associated Protein Degradation Machinery in the Human Mast Cell Leukemia Cell Line HMC-1.2. [Cells. 2024]
TurboID-Based IRE1 Interactome Reveals Participants of the Endoplasmic Reticulum-Associated Protein Degradation Machinery in the Human Mast Cell Leukemia Cell Line HMC-1.2.
Ahmed N, Preisinger C, Wilhelm T, Huber M. Cells. 2024 Apr 25; 13(9). Epub 2024 Apr 25.
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells. [Endocr Regul. 2024]
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells.
Minchenko OH, Sliusar MY, Khita OO, Minchenko DO, Viletska YM, Halkin OV, Levadna LO, Cherednychenko AA, Khikhlo YP. Endocr Regul. 2024 Jan 1; 58(1):91-100. Epub 2024 Apr 24.
IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response. [J Cell Biol. 2024]
IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response.
Simpson MS, De Luca H, Cauthorn S, Luong P, Udeshi ND, Svinkina T, Schmieder SS, Carr SA, Grey MJ, Lencer WI. J Cell Biol. 2024 Jul 1; 223(7). Epub 2024 Apr 5.

RefSeq protein
See the reference protein sequence for serine/threonine-protein kinase/endoribonuclease IRE1 precursor (NP_001424.3).

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Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
O75460 [Domain Mapping of Disease Mut...]
O75460
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE1; AltName: Fu...
RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE1; AltName: Full=Endoplasmic reticulum-to-nucleus signaling 1; AltName: Full=Inositol-requiring protein 1; Short=hIRE1p; AltName: Full=Ire1-alpha; Short=IRE1a; Includes: RecName: Full=Serine/threonine-protein kinase; Includes: RecName: Full=Endoribonuclease; Flags: Precursor
gi|193806335|sp|O75460.2|ERN1_HUMAN

Protein
C0543697 (0)
MedGen
Waldenstrom macroglobulinemia
Waldenstrom macroglobulinemia

MedGen
C0024419[conceptid] (1)
MedGen

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Protein