RecName: Full=NAD(+) hydrolase SARM1; Short=NADase SARM1; Short=hSARM1 - Protein

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The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products. [PLoS One. 2024]
The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products.
Garb J, Amitai G, Lu A, Ofir G, Brandis A, Mehlman T, Kranzusch PJ, Sorek R. PLoS One. 2024; 19(4):e0302251. Epub 2024 Apr 18.
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels. [J Biol Chem. 2023]
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels.
Icso JD, Thompson PR. J Biol Chem. 2023 Nov; 299(11):105284. Epub 2023 Sep 22.
Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival. [Sci Rep. 2022]
Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival.
Ademi M, Yang X, Coleman MP, Gilley J. Sci Rep. 2022 Aug 16; 12(1):13846. Epub 2022 Aug 16.

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Q6SZW1 [Domain Mapping of Disease Mut...]
Q6SZW1
Domain Mapping of Disease Mutations
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RecName: Full=NAD(+) hydrolase SARM1; Short=NADase SARM1; Short=hSARM1; AltName:...
RecName: Full=NAD(+) hydrolase SARM1; Short=NADase SARM1; Short=hSARM1; AltName: Full=NADP(+) hydrolase SARM1; AltName: Full=Sterile alpha and Armadillo repeat protein; AltName: Full=Sterile alpha and TIR motif-containing protein 1; AltName: Full=Sterile alpha motif domain-containing protein 2; Short=MyD88-5; Short=SAM domain-containing protein 2; AltName: Full=Tir-1 homolog; Short=HsTIR; Flags: Precursor
gi|83288284|sp|Q6SZW1.1|SARM1_HUMAN

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Homologene neighbors for GEO Profiles (Select 83898768) (0)
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Chromosome neighbors for GEO Profiles (Select 83898770) (20)
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Chromosome neighbors for GEO Profiles (Select 83898765) (20)
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