RecName: Full=E3 ubiquitin-protein ligase NEDD4-like; AltName: Full=HE - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

E3 ligase Nedd4L promotes macrophage M1 polarization and exacerbates brain damage by TRAF3/TBK1 signaling pathway after ICH in mice. [Immunol Lett. 2023]
E3 ligase Nedd4L promotes macrophage M1 polarization and exacerbates brain damage by TRAF3/TBK1 signaling pathway after ICH in mice.
Xia X, Yang Z, Zhang J, Fu X, Han B, Xiong Q, Yu A. Immunol Lett. 2023 Dec; 264:36-45. Epub 2023 Nov 6.
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures. [Front Mol Neurosci. 2022]
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Liu X, Zhang L, Zhang H, Liang X, Zhang B, Tu J, Zhao Y. Front Mol Neurosci. 2022; 15:919718. Epub 2022 Jun 27.
The Antidiabetic Drug Metformin Regulates Voltage-Gated Sodium Channel Na(V)1.7 via the Ubiquitin-Ligase NEDD4-2. [eNeuro. 2022]
The Antidiabetic Drug Metformin Regulates Voltage-Gated Sodium Channel Na(V)1.7 via the Ubiquitin-Ligase NEDD4-2.
Deftu AF, Chu Sin Chung P, Laedermann CJ, Gillet L, Pertin M, Kirschmann G, Decosterd I. eNeuro. 2022 Mar-Apr; 9(2). Epub 2022 Mar 4.

RefSeq protein isoforms
See 41 reference sequence protein isoforms for the Nedd4l gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=E3 ubiquitin-protein ligase NEDD4-like; AltName: Full=HECT-type E3...
RecName: Full=E3 ubiquitin-protein ligase NEDD4-like; AltName: Full=HECT-type E3 ubiquitin transferase NED4L; AltName: Full=NEDD4.2; AltName: Full=Nedd4-2
gi|73921205|sp|Q8CFI0.2|NED4L_MOUSE

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein