RecName: Full=Eukaryotic translation initiation factor 2 subunit 3; Al - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

mRNA analysis revealed a novel pathogenic EIF2S3 variant causing MEHMO syndrome. [Eur J Med Genet. 2022]
mRNA analysis revealed a novel pathogenic EIF2S3 variant causing MEHMO syndrome.
Ivanova N, Serzhanova V, Demina N, Guseva D, Skoblov M. Eur J Med Genet. 2022 Feb; 65(2):104421. Epub 2022 Jan 7.
Eukaryotic initiation factor-2, gamma subunit, suppresses proliferation and regulates the cell cycle via the MAPK/ERK signaling pathway in acute myeloid leukemia. [J Cancer Res Clin Oncol. 2021]
Eukaryotic initiation factor-2, gamma subunit, suppresses proliferation and regulates the cell cycle via the MAPK/ERK signaling pathway in acute myeloid leukemia.
Lu J, Chen S, Tan H, Huang Z, Li B, Liu L, Chen Y, Zeng X, Zou Y, Xu L. J Cancer Res Clin Oncol. 2021 Nov; 147(11):3157-3168. Epub 2021 Jul 7.
Novel pathogenic EIF2S3 missense variants causing clinically variable MEHMO syndrome with impaired eIF2γ translational function, and literature review. [Clin Genet. 2020]
Novel pathogenic EIF2S3 missense variants causing clinically variable MEHMO syndrome with impaired eIF2γ translational function, and literature review.
Kotzaeridou U, Young-Baird SK, Suckow V, Thornburg AG, Wagner M, Harting I, Christ S, Strom T, Dever TE, Kalscheuer VM. Clin Genet. 2020 Nov; 98(5):507-514. Epub 2020 Sep 4.

RefSeq genomic sequence
See the genomic reference sequence for the EIF2S3 gene (NG_016387.1).
RefSeq protein
See the reference protein sequence for eukaryotic translation initiation factor 2 subunit 3 (NP_001406.1).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

P41091 [Domain Mapping of Disease Mut...]
P41091
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Eukaryotic translation initiation factor 2 subunit 3; AltName: Ful...
RecName: Full=Eukaryotic translation initiation factor 2 subunit 3; AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma X; Short=eIF2-gamma X; Short=eIF2gX
gi|729816|sp|P41091.3|IF2G_HUMAN

Protein
EFHC2 EF-hand domain containing 2 [Homo sapiens]
EFHC2 EF-hand domain containing 2 [Homo sapiens]
Gene ID:80258

Gene

Your browsing activity is empty.

Activity recording is turned off.

Protein