gamma-secretase subunit APH-1A [Rattus norvegicus]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

[Effect of βsheet blocking peptide H102 on APP metabolic enzymes in hippocampal brain of double transgenic AD mice]. [Zhongguo Ying Yong Sheng Li Xu...]
[Effect of βsheet blocking peptide H102 on APP metabolic enzymes in hippocampal brain of double transgenic AD mice].
Jiang F, Sun FX, Xu SM. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Apr 8; 33(4):299-303.
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria. [J Biol Chem. 2004]
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.
Hansson CA, Frykman S, Farmery MR, Tjernberg LO, Nilsberth C, Pursglove SE, Ito A, Winblad B, Cowburn RF, Thyberg J, et al. J Biol Chem. 2004 Dec 3; 279(49):51654-60. Epub 2004 Sep 28.
Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney. [Development. 2003]
Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney.
Cheng HT, Miner JH, Lin M, Tansey MG, Roth K, Kopan R. Development. 2003 Oct; 130(20):5031-42.

RefSeq mRNA
See reference mRNA sequence for the Aph1a gene (NM_001014255.1).
RefSeq protein isoforms
See the other reference sequence protein isoform for the Aph1a gene (XP_006233039.1).

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
OMIM
OMIM records associated with protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

gamma-secretase subunit APH-1A [Rattus norvegicus]
gamma-secretase subunit APH-1A [Rattus norvegicus]
gi|62079241|ref|NP_001014277.1|

Protein
Fasting hypoglycemia
Fasting hypoglycemia

MedGen
esv3633557 (1)
dbVar

Your browsing activity is empty.

Activity recording is turned off.

Protein