RecName: Full=Cytochrome P450 4F3; AltName: Full=20-hydroxyeicosatetra - Protein

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A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer. [J Cachexia Sarcopenia Muscle. ...]
A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer.
Smeets E, Huang S, Lee XY, Van Nieuwenhove E, Helsen C, Handle F, Moris L, El Kharraz S, Eerlings R, Devlies W, et al. J Cachexia Sarcopenia Muscle. 2022 Aug; 13(4):2242-2253. Epub 2022 Jun 9.
Genetic Polymorphisms in Fatty Acid Metabolism Modify the Association Between Dietary n3: n6 Intake and Risk of Ulcerative Colitis: A Prospective Cohort Study. [Inflamm Bowel Dis. 2017]
Genetic Polymorphisms in Fatty Acid Metabolism Modify the Association Between Dietary n3: n6 Intake and Risk of Ulcerative Colitis: A Prospective Cohort Study.
Ananthakrishnan AN, Khalili H, Song M, Higuchi LM, Lochhead P, Richter JM, Chan AT. Inflamm Bowel Dis. 2017 Nov; 23(11):1898-1904.
Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. [Mol Carcinog. 2017]
Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus.
Yin J, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, et al. Mol Carcinog. 2017 Jun; 56(6):1663-1672. Epub 2017 Feb 23.

RefSeq genomic sequence
See the genomic reference sequence for the CYP4F3 gene (NG_007964.2).
RefSeq protein isoforms
See 10 reference sequence protein isoforms for the CYP4F3 gene.

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Q08477 [Domain Mapping of Disease Mut...]
Q08477
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
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RecName: Full=Cytochrome P450 4F3; AltName: Full=20-hydroxyeicosatetraenoic acid...
RecName: Full=Cytochrome P450 4F3; AltName: Full=20-hydroxyeicosatetraenoic acid synthase; Short=20-HETE synthase; AltName: Full=CYPIVF3; AltName: Full=Cytochrome P450-LTB-omega; AltName: Full=Docosahexaenoic acid omega-hydroxylase CYP4F3; AltName: Full=Leukotriene-B(4) 20-monooxygenase 2; AltName: Full=Leukotriene-B(4) omega-hydroxylase 2
gi|56757430|sp|Q08477.2|CP4F3_HUMAN

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