RecName: Full=Insulin-like growth factor-binding protein complex acid - Protein

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Clinical and biochemical characteristics and bone mineral density of homozygous, compound heterozygous and heterozygous carriers of three novel IGFALS mutations. [Eur J Endocrinol. 2017]
Clinical and biochemical characteristics and bone mineral density of homozygous, compound heterozygous and heterozygous carriers of three novel IGFALS mutations.
Işık E, Haliloglu B, van Doorn J, Demirbilek H, Scheltinga SA, Losekoot M, Wit JM. Eur J Endocrinol. 2017 Jun; 176(6):657-667. Epub 2017 Mar 1.
Assessment of pathogenicity of natural IGFALS gene variants by in silico bioinformatics tools and in vitro functional studies. [Mol Cell Endocrinol. 2016]
Assessment of pathogenicity of natural IGFALS gene variants by in silico bioinformatics tools and in vitro functional studies.
Martucci LC, Gutiérrez ML, Karabatas LM, Scaglia PA, Rey RA, Domené HM, Jasper HG, Domené S. Mol Cell Endocrinol. 2016 Jul 5; 429:19-28. Epub 2016 Mar 25.
[Structure and function of insulin-like growth factor acid-labile subunits in mammalian homologues]. [Yi Chuan. 2015]
[Structure and function of insulin-like growth factor acid-labile subunits in mammalian homologues].
Li GL, Niu LL, Liu HF, Guo JZ. Yi Chuan. 2015 Dec; 37(12):1185-93.

RefSeq genomic sequence
See the genomic reference sequence for the IGFALS gene (NG_011778.1).

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P35858 [Domain Mapping of Disease Mut...]
P35858
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
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Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Insulin-like growth factor-binding protein complex acid labile sub...
RecName: Full=Insulin-like growth factor-binding protein complex acid labile subunit; Short=ALS; Flags: Precursor
gi|543800|sp|P35858.1|ALS_HUMAN

Protein
Chain A, E3 ubiquitin-protein ligase Mdm2
Chain A, E3 ubiquitin-protein ligase Mdm2
gi|114794117|pdb|2GV2|A

Protein
Muscle, Smooth
Muscle, Smooth
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cell...<br/>

MeSH
Patellar Ligament
Patellar Ligament
A band of fibrous tissue that attaches the apex of the PATELLA to the lower part of the tubercle of the TIBIA. The ligament is actually the caudal continuation of the common t...<br/>Year introduced: 1994

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Protein