RecName: Full=Bifunctional polynucleotide phosphatase/kinase; AltName: - Protein

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Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathways. [Nucleic Acids Res. 2024]
Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathways.
Islam A, Chakraborty A, Sarker AH, Aryal UK, Pan L, Sharma G, Boldogh I, Hazra T. Nucleic Acids Res. 2024 Mar 21; 52(5):2416-2433.
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans. [J Biol Chem. 2023]
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans.
Islam A, Chakraborty A, Gambardella S, Campopiano R, Sarker AH, Boldogh I, Hazra T. J Biol Chem. 2023 May; 299(5):104714. Epub 2023 Apr 13.
Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP. [J Virol. 2022]
Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP.
Rychlowska M, Agyapong A, Weinfeld M, Schang LM. J Virol. 2022 May 11; 96(9):e0033322. Epub 2022 Apr 12.

RefSeq genomic sequence
See the genomic reference sequence for the PNKP gene (NG_027717.1).
RefSeq protein
See the reference protein sequence for bifunctional polynucleotide phosphatase/kinase (NP_009185.2).

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Q96T60 [Domain Mapping of Disease Mut...]
Q96T60
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Bifunctional polynucleotide phosphatase/kinase; AltName: Full=DNA ...
RecName: Full=Bifunctional polynucleotide phosphatase/kinase; AltName: Full=DNA 5'-kinase/3'-phosphatase; AltName: Full=Polynucleotide kinase-3'-phosphatase; Includes: RecName: Full=Polynucleotide 3'-phosphatase; AltName: Full=2'(3')-polynucleotidase; Includes: RecName: Full=Polynucleotide 5'-hydroxyl-kinase
gi|50401132|sp|Q96T60.1|PNKP_HUMAN

Protein
Rph3a rabphilin 3A [Rattus norvegicus]
Rph3a rabphilin 3A [Rattus norvegicus]
Gene ID:171039

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Protein