RecName: Full=HLA class II histocompatibility antigen gamma chain; Alt - Protein

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CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors. [Cancer Immunol Immunother. 2024]
CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors.
Wang J, Li X, Xiao G, Desai J, Frentzas S, Wang ZM, Xia Y, Li B. Cancer Immunol Immunother. 2024 Jan 27; 73(2):36. Epub 2024 Jan 27.
Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients. [Front Immunol. 2023]
Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients.
Westmeier J, Brochtrup A, Paniskaki K, Karakoese Z, Werner T, Sutter K, Dolff S, Limmer A, Mittermüller D, Liu J, et al. Front Immunol. 2023; 14:1236374. Epub 2023 Oct 25.
Increased Expression of CD74 in Atherosclerosis Associated with Inflammatory Responses of Endothelial Cells and Macrophages. [Biochem Genet. 2024]
Increased Expression of CD74 in Atherosclerosis Associated with Inflammatory Responses of Endothelial Cells and Macrophages.
Ke K, Wu Z, Lin J, Lin L, Huang N, Yang W. Biochem Genet. 2024 Feb; 62(1):294-310. Epub 2023 Jun 19.

RefSeq genomic sequence
See the genomic reference sequence for the CD74 gene (NG_029730.1).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the CD74 gene.

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Related structures

P04233 [Domain Mapping of Disease Mut...]
P04233
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=HLA class II histocompatibility antigen gamma chain; AltName: Full...
RecName: Full=HLA class II histocompatibility antigen gamma chain; AltName: Full=HLA-DR antigens-associated invariant chain; AltName: Full=Ia antigen-associated invariant chain; Short=Ii; AltName: CD_antigen=CD74; Contains: RecName: Full=Class-II-associated invariant chain peptide; Short=CLIP
gi|20178292|sp|P04233.3|HG2A_HUMAN

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