RecName: Full=Palmitoleoyl-protein carboxylesterase NOTUM; AltName: Fu - Protein

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NOTUM plays a bidirectionally modulatory role in the odontoblastic differentiation of human stem cells from the apical papilla through the WNT/β-catenin signaling pathway. [Arch Oral Biol. 2024]
NOTUM plays a bidirectionally modulatory role in the odontoblastic differentiation of human stem cells from the apical papilla through the WNT/β-catenin signaling pathway.
Zhao Q, Ren H, Wang N, Yuan X, Zhao Y, Wen Q. Arch Oral Biol. 2024 Apr; 160:105896. Epub 2024 Jan 20.
Notum enhances gastric cancer stem-like cell properties through upregulation of Sox2 by PI3K/AKT signaling pathway. [Cell Oncol (Dordr). 2024]
Notum enhances gastric cancer stem-like cell properties through upregulation of Sox2 by PI3K/AKT signaling pathway.
Liu Y, Chen H, Xiao L, Dong P, Ma Y, Zhou Y, Yang J, Bian B, Xie G, Chen L, et al. Cell Oncol (Dordr). 2024 Apr; 47(2):463-480. Epub 2023 Sep 26.
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β. [Int J Biochem Cell Biol. 2022]
Notum leads to potential pro-survival of OSCC through crosstalk between Shh and Wnt/β-catenin signaling via p-GSK3β.
Yang P, Li C, Zhou Q, Zhang X, Kou Y, Feng Q, Wang H, Su R, Hasegawa T, Liu H, et al. Int J Biochem Cell Biol. 2022 Dec; 153:106316. Epub 2022 Oct 22.

RefSeq protein
See the reference protein sequence for palmitoleoyl-protein carboxylesterase NOTUM precursor (NP_848588.3).

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Q6P988 [Domain Mapping of Disease Mut...]
Q6P988
Domain Mapping of Disease Mutations
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reagents
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RecName: Full=Palmitoleoyl-protein carboxylesterase NOTUM; AltName: Full=hNOTUM;...
RecName: Full=Palmitoleoyl-protein carboxylesterase NOTUM; AltName: Full=hNOTUM; Flags: Precursor
gi|182628300|sp|Q6P988.2|NOTUM_HUMA

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