RecName: Full=Caspase-4; Short=CASP-4; AltName: Full=ICE and Ced-3 hom - Protein

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Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome. [mSphere. 2023]
Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome.
Kroken AR, Klein KA, Mitchell PS, Nieto V, Jedel EJ, Evans DJ, Fleiszig SMJ. mSphere. 2023 Oct 24; 8(5):e0035123. Epub 2023 Aug 17.
Caspase-4/11 is critical for angiogenesis by repressing Notch1 signalling via inhibiting γ-secretase activity. [Br J Pharmacol. 2022]
Caspase-4/11 is critical for angiogenesis by repressing Notch1 signalling via inhibiting γ-secretase activity.
Fan L, Liu H, Zhu G, Singh S, Yu Z, Wang S, Luo H, Liu S, Xu Y, Ge J, et al. Br J Pharmacol. 2022 Oct; 179(20):4809-4828. Epub 2022 Jul 24.
Expression of human caspase-4 in the gingival epithelium affected with periodontitis: Its involvement in Porphyromonas gingivalis-challenged gingival epithelial cells. [Arch Oral Biol. 2022]
Expression of human caspase-4 in the gingival epithelium affected with periodontitis: Its involvement in Porphyromonas gingivalis-challenged gingival epithelial cells.
Kantrong N, Buranaphatthana W, Hormdee D, Suwannarong W, Chaichit R, Pattanaporn K, Klanrit P, Krisanaprakornkit S. Arch Oral Biol. 2022 Aug; 140:105466. Epub 2022 May 24.

RefSeq protein isoforms
See 4 reference sequence protein isoforms for the CASP4 gene.

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P49662 [Domain Mapping of Disease Mut...]
P49662
Domain Mapping of Disease Mutations
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Caspase-4; Short=CASP-4; AltName: Full=ICE and Ced-3 homolog 2; Sh...
RecName: Full=Caspase-4; Short=CASP-4; AltName: Full=ICE and Ced-3 homolog 2; Short=ICH-2; AltName: Full=ICE(rel)-II; AltName: Full=Mih1; AltName: Full=Protease TX; Contains: RecName: Full=Caspase-4 subunit p10; Contains: RecName: Full=Caspase-4 subunit p20; Flags: Precursor
gi|1812588776|sp|P49662.1|CASP4_HUM

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