RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumo - Protein

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TM9SF4 is an F-actin disassembly factor that promotes tumor progression and metastasis. [Nat Commun. 2022]
TM9SF4 is an F-actin disassembly factor that promotes tumor progression and metastasis.
Meng Z, Li Z, Xie M, Yu H, Jiang L, Yao X. Nat Commun. 2022 Sep 29; 13(1):5728. Epub 2022 Sep 29.
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells. [Oncogene. 2019]
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Zhu Y, Xie M, Meng Z, Leung LK, Chan FL, Hu X, Chi K, Liu C, Yao X. Oncogene. 2019 Jul; 38(29):5778-5791. Epub 2019 Jun 27.
TM9SF4 levels determine sorting of transmembrane domains in the early secretory pathway. [J Cell Sci. 2018]
TM9SF4 levels determine sorting of transmembrane domains in the early secretory pathway.
Vernay A, Lamrabet O, Perrin J, Cosson P. J Cell Sci. 2018 Nov 5; 131(21). Epub 2018 Nov 5.

RefSeq protein isoforms
See 8 reference sequence protein isoforms for the TM9SF4 gene.

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Q92544 [Domain Mapping of Disease Mut...]
Q92544
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibal...
RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibalism associated protein 1; Flags: Precursor
gi|172045829|sp|Q92544.2|TM9S4_HUMA

Protein
Chain A, SLIT-ROBO Rho GTPase-activating protein 2
Chain A, SLIT-ROBO Rho GTPase-activating protein 2
gi|946926028|pdb|4RUG|A

Protein
Oncolytic Virotherapy
Oncolytic Virotherapy
Use of attenuated VIRUSES as ANTINEOPLASTIC AGENTS to selectively kill CANCER cells.<br/>Year introduced: 2006

MeSH
Radiotherapy, Image-Guided
Radiotherapy, Image-Guided
The use of pre-treatment imaging modalities to position the patient, delineate the target, and align the beam of radiation to achieve optimal accuracy and reduce radiation dam...<br/>Year introduced: 2012

MeSH
Radioimmunotherapy
Radioimmunotherapy
Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-...<br/>Year introduced: 1992

MeSH

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Protein