RecName: Full=Solute carrier family 12 member 2; AltName: Full=Basolat - Protein

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Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer. [Sci Rep. 2024]
Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer.
Chen DY, Zhang YY, Nie HH, Wang HZ, Qiu PS, Wang F, Peng YN, Xu F, Zhao Q, Zhang M. Sci Rep. 2024 Feb 23; 14(1):4459. Epub 2024 Feb 23.
Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. [EMBO J. 2022]
Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Neumann C, Rosenbaek LL, Flygaard RK, Habeck M, Karlsen JL, Wang Y, Lindorff-Larsen K, Gad HH, Hartmann R, Lyons JA, et al. EMBO J. 2022 Dec 1; 41(23):e110169. Epub 2022 Oct 14.
Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment. [J Hum Genet. 2021]
Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment.
Adadey SM, Schrauwen I, Aboagye ET, Bharadwaj T, Esoh KK, Basit S, Acharya A, Nouel-Saied LM, Liaqat K, Wonkam-Tingang E, et al. J Hum Genet. 2021 Dec; 66(12):1169-1175. Epub 2021 Jul 5.

RefSeq genomic sequence
See the genomic reference sequence for the SLC12A2 gene (NG_042286.1).
RefSeq protein isoforms
See 8 reference sequence protein isoforms for the SLC12A2 gene.

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Related structures

P55011 [Domain Mapping of Disease Mut...]
P55011
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Solute carrier family 12 member 2; AltName: Full=Basolateral Na-K-...
RecName: Full=Solute carrier family 12 member 2; AltName: Full=Basolateral Na-K-Cl symporter; AltName: Full=Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
gi|1709292|sp|P55011.1|S12A2_HUMAN

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