RecName: Full=2-oxoadipate dehydrogenase complex component E1; Short=E - Protein

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CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model. [Acta Neuropathol Commun. 2020]
CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model.
Luan CJ, Guo W, Chen L, Wei XW, He Y, Chen Y, Dang SY, Prior R, Li X, Kuang Y, et al. Acta Neuropathol Commun. 2020 Mar 13; 8(1):32. Epub 2020 Mar 13.
DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo. [Hum Mol Genet. 2020]
DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo.
Leandro J, Dodatko T, Aten J, Nemeria NS, Zhang X, Jordan F, Hendrickson RC, Sanchez R, Yu C, DeVita RJ, et al. Hum Mol Genet. 2020 May 8; 29(7):1168-1179.
Genetic determinants of micronucleus formation in vivo. [Nature. 2024]
Genetic determinants of micronucleus formation in vivo.
Adams DJ, Barlas B, McIntyre RE, Salguero I, van der Weyden L, Barros A, Vicente JR, Karimpour N, Haider A, Ranzani M, et al. Nature. 2024 Mar; 627(8002):130-136. Epub 2024 Feb 14.

RefSeq protein isoforms
See 8 reference sequence protein isoforms for the Dhtkd1 gene.

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Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
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RecName: Full=2-oxoadipate dehydrogenase complex component E1; Short=E1a; Short=...
RecName: Full=2-oxoadipate dehydrogenase complex component E1; Short=E1a; Short=OADC-E1; Short=OADH-E1; AltName: Full=2-oxoadipate dehydrogenase, mitochondrial; AltName: Full=Alpha-ketoadipate dehydrogenase; Short=Alpha-KADH-E1; AltName: Full=Dehydrogenase E1 and transketolase domain-containing protein 1; AltName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; Flags: Precursor
gi|160151263|sp|A2ATU0.1|DHTK1_MOUS

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